Mercantile Bank was a historic British bank founded in 1853, and later acquired by HSBC in 1959.
It may also refer to;
- Mercantile Bank Limited, South Africa, a bank headquartered in Sandown, Gauteng, South Africa; which commenced operation in 1987 and operates under the bank holding company - Mercantile Bank Holdings Limited.
- Mercantile Bank of South Financial Group, a bank operating under the bank holding company - South Financial Group, which was acquired in 2010 by TD Bank Financial Group and subsequently renamed to TD Bank on 13 June, 2011
- Mercantile Bancorporation, a former bank holding company in Missouri, which was acquired by Firstar Corporation in 1999
- Mercantile Bank Limited, Bangladesh, a bank headquartered in Dhaka, Bangladesh and commenced operation on 2 June, 1999
- Mercantile Discount Bank, a major commercial bank in Israel.
